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Why Does Psychosis Get Worse at Night?
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Psychosis, characterized by hallucinations, delusions, and disorganized thinking, often intensifies at night a phenomenon called nocturnal exacerbation or "sun downing" in related conditions like dementia. Several interconnected factors explain this pattern, supported by clinical observations and research in psychiatry.

  1. Circadian Rhythm Disruption: The body's internal clock regulates sleep-wake cycles via melatonin and cortisol. In psychotic disorders like schizophrenia, circadian misalignment is common (e.g., delayed sleep phase). A 2020 study in Schizophrenia Bulletin found disrupted CLOCK gene expression in patients, leading to heightened symptom severity when melatonin peaks at night but fails to induce calm.
  2. Reduced Sensory Input and Distractions: Daytime offers external stimuli (light, noise, social interaction) that anchor reality and suppress intrusive thoughts. At night, darkness and silence amplify internal stimuli hallucinations feel more vivid without competing inputs. Functional MRI studies show hyperactive default mode networks in psychosis, which ramp up in low-stimulation environments.
  3. Fatigue and Neurochemical Imbalance: Accumulated daily stress depletes dopamine regulation. Evening cortisol dips can paradoxically trigger dopamine surges in vulnerable brains, worsening positive symptoms (hallucinations/delusions). Sleep deprivation from insomnia prevalent in 80% of schizophrenia cases per NIMH data further erodes prefrontal cortex inhibition, escalating paranoia.
  4. Environmental and Psychological Triggers: Dim lighting casts shadows that mimic threats; isolation heightens fear. Medications like antipsychotics may wear off by evening if not timed properly.

Management includes consistent sleep hygiene, evening light therapy, adjusted dosing, and CBT for psychosis. Consult a psychiatrist if symptoms worsen nocturnally early intervention prevents crises